Sodium Butyrate Pure USP Feed Grade Manufacturers

Anmol Chemicals is the pioneer manufacturers of Sodium Butyrate , Pharmaceutical Excipients Fragrance Food & Flavor chemicals in India. We offer Halal and Kosher Sodium Butyrate made in an ISO9001, ISO22000 (FSSC22000) cGMP and GLP certified facility. Our group has several manufacturing facilities spread across the world, supported by toll manufacturers and representatives in UAE, Europe, Africa, USA, China and has several associated manufacturing facilities spread across India. All the Information on Physics, Chemistry, Applications, Uses and Technology on Manufacture of Sodium Butyrate is in these pages.

The units have one or more of the certifications like FDA GMP, ISO 9001, ISO 22000, HACCP, REACH, Kosher & Halal

Sodium Butyrate Pure Feed Grade and USP Manufacturers

Sodium Butyrate CAS Number 156-54-7, EINECS EC Number 205-857-6, HS Code 291560**, Molecular Weight 110.09, Chemical Formula CH3CH2CH2COONa

We also offer Coated or Encapsulated Sodium Butyrate Encapsulated for Time Release or Slow Release

Introduction: Sodium butyrate is a short chain fatty acid that has effects at the molecular, cellular, and tissue level. It has long been known as an inhibitor of histone deacetylases (HDACs). In cells, this alters the expression of a select group of genes containing butyrate response elements and may also involve Sp1/Sp3 binding sites. Sodium butyrate also induces growth arrest, differentiation and apoptosis in cancer cells, primarily through its effects on HDAC activity. In addition, it suppresses inflammation, in part by reducing the expression of pro-inflammatory cytokines, including interferon-γ, interleukin (IL)-6, and, and IL-1β.

Sodium butyrate is the product that energy nutrition adjusts technology of intestinal mucosa. It is an energy source of rapid proliferation of intestinal mucosa epithelial cell, activatory lymphocyte etc., which can ensure the rapid repair of injured intestinal mucosa and accelerate proliferation and maturation. It can promote the growth of beneficial bacteria Lactobacillus, bifidobacterium and inhibit the growth of harmful bacteria Coliform in the gastrointestinal tract. In essence, reduce the diarrhea and promote the brood growth rapidly. In addition to its antineoplastic activity, sodium butyrate induces changes in cellular morphology, alters the expression of cellular genes, modulates hormone action and hormone receptors as well as growth factor receptors. Sodium butyrate has also been shown to inhibit the high fat diet-induced mammary tumorigenesis. Additionally, sodium butyrate has been used in preliminary clinical trails to treat certain acute leukemias and stable butyrate derivatives are developed with a view to use these compounds to treat mammary carcinoma.

1. Sodium butyrate has hydrophilic and lipophilic properties. It can promote the growth of beneficial bacteria and inhibit the growth of harmful bacteria in the gastrointestinal tract. Sodium butyrate is an energy source of enterocyte, which can promote growth of intestinal mucosa. Villus of intestine increase 30%
2. Sodium butyrate is an energy source of cell differentiation, which can ensure the rapid repair of injured chorion and accelerate proliferation and maturation of gastrointestinal cells.
3. Improve animal immune status.
4. Increase the absorption area of small intestine, promote the absorption of calcium, and stimulate the secretion of digestive enzymes in the gastrointestinal tract and pancreas.
5. Sodium butyrate is a good attractant which can significantly increase feed intake. Regulate intestinal micro-ecological balance.
6. Sodium butyrate can improve the health and growth performance of animals and increase economic benefits for farmers. It can significantly increase feed intake and reduce PH value of gastrointestinal tract. The effect is obvious that inhibits harmful bacteria and promotes the growth of animal.

Application: Feed additive for porket, growing pig, layer, meat chicken, fish and other animals.

Usage and Dosage
The dosage is only for guidance to starters. The best dosage is the one that suits the environment.

1. For pigs kg per ton of complete feed.
Porkets ............ 1.0-1.5
Piglets .............. 0.5-1.0
Growing pigs .... 0.25-0.5
Finishing pigs .... 0.25-0.5
Boar ................. 0.5-1.0

2. For poultry kg per ton of complete feed
Broilers (1-21d) .......................................... 0.15-0.5
Broilers (22-40d) ........................................ 0.10-0.30
Broilers (41- time of slaughter) Laying hens .. 0.15-0.30
Broiler breeders ........................................... 0.25-0.40
Broiler breeders ........................................... 0.3-0.6

3. Others kg per ton of complete feed
Rabbits ......................... 1.5
Fishes ........................... 2.0-3.0
Calves .......................... 1.5-2.0

Sodium Butyrate USP
C4H7NaO2 -- 110.10
Butyric acid, sodium salt.
CAS Number 156-54-7

Sodium Butyrate contains not less than 98.0 percent and not more than 101.0 percent of C4H7NaO2, calculated on the anhydrous basis.

Identification:
A: Infrared Absorption on the undried specimen.
B: A solution (1 in 10) meets the requirements of the tests for Sodium..
Alkalinity: Dissolve 2.0 g in 20 mL of water, and add 1 drop of phenolphthalein TS: if a pink color is produced, it is discharged by 0.50 mL of 0.10 N sulfuric acid.
Water: not more than 1.0%.
Heavy metals: 0.001%.
Assay: Dissolve about 200 mg of Sodium Butyrate, accurately weighed, in 50 mL of glacial acetic acid. Add 1 drop of crystal violet TS, and titrate with 0.1 N perchloric acid to a green endpoint. Perform a blank determination, and make any necessary correction. Each mL of 0.1 N perchloric acid is equivalent to 11.01 mg of C4H7NaO2.

Anmol Chemicals
S-8, SARIFA MANSION, 2ND FLANK ROAD, CHINCHBUNDER, MUMBAI 400009, INDIA
TEL: (OFFICE) 91-22-23770100, 23726950, 23774610, 23723564. FAX: 91-22-23728264

Exports to USA, Canada, UAE, Dubai, South Africa, Tanzania, Kenya, Nigeria, Egypt, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Europe Netherlands, Italy, Spain, Germany, Portugal, France, Malaysia, Indonesia, Thailand, Georgia, Korea, Japan, etc.

ITEM	SPECIFICATION
Assay	%≥ 99
Solubility in Water	≤ Slightly Turbid
Free Acid as CH3COOH	%≤ 0.11
Free Base as NA2CO3	%≤ 0.16
Loss on Drying	%≤ 5
Heavy metals as Pb	%≤ 0.002
Arsenic as As	%≤ 0.0002